Physician Assistant Jobs in San Antonio, TX

San Antonio, Texas$101,250 USD/yearFull-time
Updated: June 2026Expert reviewed|Data sourced from BLS, Glassdoor, and industry reports

About Physician Assistant Jobs in San Antonio

Looking for a Physician Assistant job in San Antonio? You're in the right place. This guide covers everything you need to know about working as a Physician Assistant in San Antonio, TX.

We'll show you what you can expect to earn. We'll also share which companies are hiring. Plus, you'll learn about the cost of living and how to get started in your job search.

San Antonio has a strong job market for Physician Assistants. Many employers are actively looking for talent. Read on to learn how to land your next role.

Physician Assistant Salary in San Antonio

Entry Level
$72,675
Median
$101,250
Senior Level
$134,550

Physician Assistant salaries in San Antonio are in line with national averages, offering competitive compensation for the region.

Purchasing power in San Antonio is comparable to the national average, with salaries appropriately scaled to local costs.

Required Skills

Clinical AssessmentDiagnosisTreatmentProceduresPatient Care

Physician Assistant Job Market in San Antonio

San Antonio, TX is a major regional employment hub for Physician Assistant professionals. With a population of 1.5 million, the San Antonio-New Braunfels metro area offers diverse opportunities across multiple industries. The city's strong Military and Healthcare sectors create robust demand for Physician Assistant talent. The market for Physician Assistant positions remains stable, with opportunities in both established companies and growing organizations.

What it's like to job-hunt for Physician Assistant roles in San Antonio

San Antonio's Military sector is one of the leading employers of Physician Assistants in Texas. With approximately 1,547,253 residents in the metro area, the Physician Assistant job market here is shaped by long-established firms in Military and Healthcare alongside a growing roster of newer entrants.

Physician Assistant salaries in San Antonio center around $101,250 per year. The local cost-of-living index of 90 sits close to the national average, so the salary's real purchasing power is essentially what the headline number suggests. This makes San Antonio an attractive market for Physician Assistant candidates relocating from higher-cost coastal cities.

Physician Assistant demand in San Antonio has been relatively stable over the past 2-3 years. Net hiring is largely backfill-driven rather than expansion, which means each opening is more competitive but also more durable. Senior candidates with established local networks have the strongest advantage.

Hybrid arrangements have become the norm for Physician Assistant roles in San Antonio, with most employers expecting 2-4 days per week in the office. Fully remote variants exist but are usually reserved for senior or specialized hires. Junior candidates should expect to be on-site most of the week.

Core skills that consistently show up in San Antonio Physician Assistant postings include Clinical Assessment, Diagnosis, Treatment, and Procedures. Candidates whose resumes lead with measurable outcomes against these specific skills (project counts, quantified impact, recognized certifications) tend to move through screening faster than those leading with general experience claims.

Compensation negotiation for Physician Assistant roles in San Antonio typically has more room than candidates assume. Asking for 8-12% above the initial offer is common practice and rarely jeopardizes an offer; pairing the ask with a specific outside reference point (a competing offer, a published salary band) makes it more effective.

Top Companies Hiring Physician Assistants in San Antonio

University Health SystemBaptist Health SystemMethodist HealthcareChristus Santa Rosa

Major employers hiring Physician Assistants in San Antonio include University Health System, Baptist Health System, Methodist Healthcare, Christus Santa Rosa. With major hospital systems and research institutions, San Antonio offers excellent opportunities for healthcare professionals at all career stages. Many companies offer competitive benefits including comprehensive healthcare, and professional development opportunities.

Cost of Living for Physician Assistants in San Antonio

Living in San Antonio as a Physician Assistant means navigating a cost of living that's close to the national average. Average rent for a 1-bedroom apartment is approximately $1,300/month (28% below the national average). At median Physician Assistant salary, housing is quite affordable at 15% of gross income, leaving room for savings and lifestyle spending. Suburban apartments average $1,000/month, offering significant savings with slightly longer commutes.

90
Cost Index (100=avg)
$1.3K
Avg Rent/Month
Growing
Tech Hub
Tier 2
Market Size

Commuting as a Physician Assistant in San Antonio

San Antonio Limited public transit options; car recommended for most commutes. The average commute time is 25 minutes. Research employer-specific shuttle services. Consider living close to your workplace. Since transit options are limited, consider living close to your workplace or negotiating flexible hours to avoid peak traffic.

Best neighborhoods for Physician Assistants in San Antonio: Downtown (Central business district with tech companies); Tech Park/Campus (Suburban office park developments). Downtown is particularly popular among Physician Assistant professionals due to proximity to major employers and urban amenities.

Tax Considerations in Texas

Texas has no state income tax. Compared to a state with 5% income tax, a Physician Assistant earning $101,250 would save approximately $5,063 annually. This makes San Antonio attractive for high earners, though property taxes and sales tax help fund state services.

Career Outlook for Physician Assistants

The job outlook for Physician Assistants in San Antonio is stable. While not experiencing rapid growth, the field maintains steady demand with consistent opportunities for qualified professionals. San Antonio's growing economy creates new positions regularly, often with less competition than coastal tech hubs. In-demand skills include Clinical Assessment, Diagnosis, Treatment, Procedures.

Relocating to San Antonio

San Antonio's affordable cost of living means your Physician Assistant salary will stretch further than in major coastal cities. Many professionals relocate here for better quality of life. Texas has no state income tax, which can add thousands to your annual take-home pay compared to high-tax states like California or New York. Be prepared for hot summers. Air conditioning is essential, and outdoor activities shift to mornings and evenings during summer months.

Frequently Asked Questions

What is the average Physician Assistant salary in San Antonio, TX?

The average Physician Assistant salary in San Antonio, TX is $101,250 per year. Entry-level Physician Assistants typically start around $72,675, while experienced professionals can earn $134,550 or more. The national average for Physician Assistant roles is $112,500.

How many Physician Assistant jobs are available in San Antonio?

San Antonio has a strong job market with regular openings for Physician Assistant professionals. Major employers hiring Physician Assistants include University Health System, Baptist Health System, Methodist Healthcare, Christus Santa Rosa. The Military and Healthcare sectors drive much of the demand in this market.

Is San Antonio a good city for Physician Assistants?

San Antonio is an very good choice for Physician Assistants. As a major metro area, it offers abundant opportunities and competitive salaries. The affordable cost of living means salaries go further than in more expensive markets. The city's military industry creates strong demand for healthcare professionals.

What skills are most in-demand for Physician Assistants in San Antonio?

Top skills for Physician Assistants in San Antonio include Clinical Assessment, Diagnosis, Treatment, Procedures, Patient Care. Employers value both technical expertise and soft skills like communication and teamwork.

What is the cost of living for Physician Assistants in San Antonio?

San Antonio's cost of living is near the national average (90% of baseline). Average rent for a 1-bedroom apartment is approximately $1,300/month. Purchasing power in San Antonio is comparable to the national average, with salaries appropriately scaled to local costs.

How is the commute for Physician Assistants in San Antonio?

San Antonio Limited public transit options; car recommended for most commutes. The average commute is 25 minutes. Research employer-specific shuttle services.

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