Nurse Practitioner Jobs in Knoxville, TN

Knoxville, Tennessee$100,125 USD/yearFull-time
Updated: March 2026Expert reviewed|Data sourced from BLS, Glassdoor, and industry reports

Nurse Practitioner Salary in Knoxville

Entry Level
$71,868
Median
$100,125
Senior Level
$133,055

Nurse Practitioner salaries in Knoxville are 11% below the national average, though the lower cost of living often provides similar purchasing power.

Purchasing power in Knoxville is comparable to the national average, with salaries appropriately scaled to local costs.

Required Skills

Advanced PracticeDiagnosisTreatment PlanningPrescribingPatient Education

Nurse Practitioner Job Market in Knoxville

Knoxville, TN is a growing job market with increasing opportunities for Nurse Practitioner professionals. Though smaller than coastal metros, Knoxville offers focused opportunities and often better work-life balance. The city's strong Healthcare and Education sectors create robust demand for Nurse Practitioner talent. The market for Nurse Practitioner positions remains stable, with opportunities in both established companies and growing organizations.

Top Companies Hiring Nurse Practitioners in Knoxville

Local hospital systemsRegional healthcare networksPrivate medical groups

Major employers hiring Nurse Practitioners in Knoxville include Local hospital systems, Regional healthcare networks, Private medical groups. With major hospital systems and research institutions, Knoxville offers excellent opportunities for healthcare professionals at all career stages. Many companies offer competitive benefits including comprehensive healthcare, and professional development opportunities.

Cost of Living for Nurse Practitioners in Knoxville

Living in Knoxville as a Nurse Practitioner means navigating a cost of living that's below the national average, making it an attractive option for budget-conscious professionals. Average rent for a 1-bedroom apartment is approximately $1,800/month. At median Nurse Practitioner salary, housing is quite affordable at 22% of gross income, leaving room for savings and lifestyle spending. Suburban apartments average $1,400/month, offering significant savings with slightly longer commutes.

89
Cost Index (100=avg)
$1.8K
Avg Rent/Month
Growing
Tech Hub
Tier 3
Market Size

Commuting as a Nurse Practitioner in Knoxville

Knoxville Limited public transit options; car recommended for most commutes. The average commute time is 25 minutes. Research employer-specific shuttle services. Consider living close to your workplace. Since transit options are limited, consider living close to your workplace or negotiating flexible hours to avoid peak traffic.

Best neighborhoods for Nurse Practitioners in Knoxville: Downtown (Central business district with tech companies); Tech Park/Campus (Suburban office park developments). Downtown is particularly popular among Nurse Practitioner professionals due to proximity to major employers and urban amenities.

Tax Considerations in Tennessee

Tennessee has no state income tax. Compared to a state with 5% income tax, a Nurse Practitioner earning $100,125 would save approximately $5,006 annually. This makes Knoxville attractive for high earners, though property taxes and sales tax help fund state services.

Career Outlook for Nurse Practitioners

The job outlook for Nurse Practitioners in Knoxville is stable. While not experiencing rapid growth, the field maintains steady demand with consistent opportunities for qualified professionals. While the market is smaller, Knoxville offers opportunities for those seeking specialized roles or better work-life balance. In-demand skills include Advanced Practice, Diagnosis, Treatment Planning, Prescribing.

Relocating to Knoxville

Knoxville's affordable cost of living means your Nurse Practitioner salary will stretch further than in major coastal cities. Many professionals relocate here for better quality of life. Tennessee has no state income tax, which can add thousands to your annual take-home pay compared to high-tax states like California or New York.

Frequently Asked Questions

What is the average Nurse Practitioner salary in Knoxville, TN?

The average Nurse Practitioner salary in Knoxville, TN is $100,125 per year. Entry-level Nurse Practitioners typically start around $71,868, while experienced professionals can earn $133,055 or more. The national average for Nurse Practitioner roles is $112,500.

How many Nurse Practitioner jobs are available in Knoxville?

Knoxville has a growing job market with steady opportunities for Nurse Practitioner professionals. Major employers hiring Nurse Practitioners include Local hospital systems, Regional healthcare networks, Private medical groups. The Healthcare and Education sectors drive much of the demand in this market.

Is Knoxville a good city for Nurse Practitioners?

Knoxville is an solid choice for Nurse Practitioners. While not as large as coastal metros, it offers solid opportunities and often better work-life balance. The affordable cost of living means salaries go further than in more expensive markets. The city's healthcare industry creates strong demand for healthcare professionals.

What skills are most in-demand for Nurse Practitioners in Knoxville?

Top skills for Nurse Practitioners in Knoxville include Advanced Practice, Diagnosis, Treatment Planning, Prescribing, Patient Education. Employers value both technical expertise and soft skills like communication and teamwork.

What is the cost of living for Nurse Practitioners in Knoxville?

Knoxville's cost of living is below the national average (89% of baseline). Average rent for a 1-bedroom apartment is approximately $1,800/month. Purchasing power in Knoxville is comparable to the national average, with salaries appropriately scaled to local costs.

How is the commute for Nurse Practitioners in Knoxville?

Knoxville Limited public transit options; car recommended for most commutes. The average commute is 25 minutes. Research employer-specific shuttle services.

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